EVALUATION OF INTRAVENOUS AND INTRAMUSCULAR EFFICACY IN CHILDHOOD IMMUNE THROMBOCYTOPENIC PURPURA
نویسندگان
چکیده
منابع مشابه
Immune thrombocytopenic purpura of childhood.
Immune mediated thrombocytopenia (ITP) is a common manifestation of autoimmune disease in children. Although patients often present with bruises, petechiae, and some mucosal bleeding, the incidence of life-threatening hemorrhage is rare (0.2-0.9%) but can be fatal when presenting in vital organs. A wide range of therapeutic regimens are currently in use, including observation alone, as the majo...
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Abstract Objective Immune thrombocytopenic purpura (ITP) manifests as an easy bruising or extravasation of blood from capillaries into skin and mucous membranes. The characteristics of acute ITP in infants have rarely been described. In order to better understand acute ITP in infants, the characteristics of the disease at this age group was investigated. Material and Methods The present des...
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The efficacy, toxicity, and mechanism of effect of intravenous Anti-D (Winrho) were studied in 43 Rh+ patients with immune thrombocytopenia purpura (ITP) who had not undergone splenectomy and in three already splenectomized patients. The mean platelet increase for the 43 nonsplenectomized patients was 95,000/microL (median 43,000/microL). Children had greater acute platelet responses than did a...
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This study had the objective to assess the frequency of Tregs in children newly diagnosed with ITP and ascertain whether an association exists between Tregs and platelet counts, by means of a comparison with healthy controls. This case-control study included 19 patients newly diagnosed with ITP-whose blood samples were collected at four points in time: before any therapy and 1, 3, and 6 months ...
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Correspondence Long-term cost-efficacy of rituximab in immune thrombocytopenic purpura Sir, Prior to 1981, the only effective treatments for increasing platelet count in immune thrombo-cytopenic purpura (ITP) were corticosteroids and splenectomy. More recently, intravenous immuno-globulin (IVIg) and Rh immunoglobulin (IV RhIg) have demonstrated efficacy. Other treatments, including danazol, aza...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1999
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199906000-00251